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Factors released by neighbouring -cells or -cells amplify the glucose-induced effects on somatostatin secretion from -cells, which act locally within the islets as paracrine or autocrine inhibitors of insulin, glucagon and somatostatin secretion

In a rat model of DOX-induced cardiotoxicity, it has been unequivocally demonstrated that DOX induces the production of ROS and transforming growth factor-beta (TGF-), thereby promoting the transformation of cardiac fibroblasts into myofibroblasts (Tian et al., 2024)

Cell lines Human endothelial cells HUVEC (CC-Y1285) were purchased from EK-Bioscience (Shanghai, China)

Zelnickova, P., Matiasovic, J., Pavlova, B., Kudlackove, H., Kovaru, F